Sunday Dec 21, 2025

Biochemistry | Glycolysis, TCA, and Oxidative Phosphorylation

๐Ÿ In this episode of PodBites, Saad and Yahia take you on a guided journey through the cellโ€™s energy factory โ€” following glucose from entry into the cell all the way to ATP production.

๐ŸŽ™๏ธ Tune in to explore:

  • Core metabolism concepts: anabolism vs catabolism & energy charge

  • Glycolysis: key steps, regulation, and aerobic vs anaerobic fate

  • PFK-1 as the rate-limiting enzyme and hormonal control

  • Pyruvate dehydrogenase complex and why thiamine matters

  • The TCA cycle as the metabolic hub

  • Electron transport chain & oxidative phosphorylation

  • Classic inhibitors, uncouplers, and clinical correlations like lactic acidosis

๐ŸŒŸ A story-driven, exam-ready guide to understanding how cells make energy and what happens when the system breaks down.

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