Monday May 05, 2025

Adrenal Disorders

🎙️ Episode Description: Adrenal Disorders – From Hyperfunction to Hormonal Havoc

In this high-yield episode of PodBites, Amr Mohammed and Abdulrahman Farahat take you on a case-based journey through the adrenal gland—from cortisol overload to life-threatening insufficiency. Whether it’s a moon-faced patient with Cushing syndrome, a hypertensive mystery from Conn’s, or a high-stakes pheochromocytoma, this episode connects real-world clues to core pathophysiology, histology, and genetic links.

You’ll break down every layer of adrenal disease—including hyperfunction, hypofunction, androgen excess, neoplasms, pheochromocytoma, paragangliomas, MEN syndromes, and autoimmune polyglandular syndromes—complete with diagnostic algorithms, hormone clues, and high-yield practice questions.

💡 Key Highlights:
✔️ Cushing’s syndrome: ACTH-dependent vs independent + screening pearls
✔️ Hyperaldosteronism: Conn’s vs secondary + classic hypokalemia clues
✔️ Addison’s disease: electrolyte imbalances, hyperpigmentation, and APS links
✔️ CAH (21α vs 11β-hydroxylase deficiency): virilization, salt-wasting, and labs
✔️ Adrenal tumors: adenomas vs carcinomas with morphology and histology
✔️ Pheochromocytoma triad: headache, sweating, palpitations + SDH mutations
✔️ MEN syndromes and RET gene: don’t miss medullary thyroid carcinoma!
✔️ Full recap + case-based MCQs for exam mastery

🎧 Whether you're prepping for endocrine exams or just curious about why salt-craving matters—this bite-sized episode has you covered from cortex to medulla!

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