
Monday May 05, 2025
Adrenal Disorders
đď¸ Episode Description: Adrenal Disorders â From Hyperfunction to Hormonal Havoc
In this high-yield episode of PodBites, Amr Mohammed and Abdulrahman Farahat take you on a case-based journey through the adrenal glandâfrom cortisol overload to life-threatening insufficiency. Whether itâs a moon-faced patient with Cushing syndrome, a hypertensive mystery from Connâs, or a high-stakes pheochromocytoma, this episode connects real-world clues to core pathophysiology, histology, and genetic links.
Youâll break down every layer of adrenal diseaseâincluding hyperfunction, hypofunction, androgen excess, neoplasms, pheochromocytoma, paragangliomas, MEN syndromes, and autoimmune polyglandular syndromesâcomplete with diagnostic algorithms, hormone clues, and high-yield practice questions.
đĄ Key Highlights:
âď¸ Cushingâs syndrome: ACTH-dependent vs independent + screening pearls
âď¸ Hyperaldosteronism: Connâs vs secondary + classic hypokalemia clues
âď¸ Addisonâs disease: electrolyte imbalances, hyperpigmentation, and APS links
âď¸ CAH (21Îą vs 11β-hydroxylase deficiency): virilization, salt-wasting, and labs
âď¸ Adrenal tumors: adenomas vs carcinomas with morphology and histology
âď¸ Pheochromocytoma triad: headache, sweating, palpitations + SDH mutations
âď¸ MEN syndromes and RET gene: donât miss medullary thyroid carcinoma!
âď¸ Full recap + case-based MCQs for exam mastery
đ§ Whether you're prepping for endocrine exams or just curious about why salt-craving mattersâthis bite-sized episode has you covered from cortex to medulla!
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